Zide is used for the control of blood glucose in people with type 2 diabetes. It increases the amount of insulin released by the pancreas and helps the body use insulin more efficiently.
- Gliclazide…………………… 40 mg
Colour: Quinoline Yellow Lake
Dosage: As directed by the Physician.
Storage: Preserve in well-closed, light-resistant containers and store at controlled room temperature.
Manufactured by: Quest Pharmaceuticals Pvt. Ltd., Nepal.
Gliclazide is a sulfonylurea type of anti-diabetic medication, used to treat diabetes mellitus type 2. It is used when dietary changes, exercise, and weight loss are not enough. It is taken by mouth.
Zide stimulates insulin secretion from pancreatic beta-cells, reduces insulin uptake and glucose output by the liver, and increases insulin sensitivity at peripheral target sites. It decreases microthrombosis by partial inhibition of platelet aggregation and adhesion, and by restoring fibrinolysis w/ an increase in tissue plasminogen activator (t-PA) activity.
- Monitor blood glucose concentration. May require insulin during metabolic stress. Care when transferring from combination therapy. Increased risk of severe hypoglycaemia in elderly, debilitated patients, patients with hepatic or renal impairment. Risk of hypogylcaemia when caloric intake is deficient, after strenuous exercise, when taken with ethanol or when >1 antidiabetic drug is used.
The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.
Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine’s working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.