Lipta-5 is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
- Linagliptin………………. 5 mg
Colour: Red Oxide of Iron
Dosage: As directed by the Physician.
Storage: Preserve in well-closed, light-resistant containers and store at controlled room temperature
Manufactured by: Nepal Pharmaceuticals Laboratory Pvt. Ltd., Nepal.
Linagliptin is a medication used to treat diabetes mellitus type 2. It is generally less preferred than metformin and sulfonylureas as an initial treatment. It is used together with exercise and diet. It is not recommended for type 1 diabetes. It is taken by mouth.
Linagliptin is an inhibitor of DPP-4, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Metabolism of linagliptin is mediated by cytochrome P450 3A4, Aldo-keto reductases, and carbonyl reductases 2. 84.7% of linagliptin is eliminated in the feces and 5.4% is eliminated in the urine 2,3. The terminal half-life of linagliptin is 155 hours 2. Total clearance of linagliptin is 374mL/min.
Lipta -5 Common Side Effects
Some of the more common side effects that can occur with linagliptin-metformin include cold-like symptoms (stuffy or runny nose, sore throat, cough, diarrhea, decreased appetite, nausea or vomiting, itching, etc. If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Linagliptin is contraindicated in patients with a history of hypersensitivity to linagliptin, such as anaphylaxis, urticaria, angioedema, exfoliative dermatitis or other serious allergic skin condition (serious rash), or bronchial hypersensitivity.